KetoGuardian™

KetoGuardian™ uses the same ingredients as KetoSavior™ at doses appropriate for daily use. It also contains an additional ingredient that directly activates AMPK, upregulates genes that encourage burning fat for energy and downregulates genes responsible for new fat storage*.

All of the extracts in KetoGuardian™ have different actions and accomplish different goals, but put together, they are an extremely powerful supplement.

White Mulberry Leaf Extract

1-deoxynojirimycin, or DNJ, is an active ingredient found in the leaves of the white mulberry tree.  White mulberry has been used for millennia in Traditional Chinese Medicine. 

Its contribution to enhancing ketosis is through its ability to inhibit α-glucosidase, the group of chemicals the body releases to digest carbohydrates*. 

Although this doesn’t stop their digestion completely, it slows the process down to the point where it minimizes the spike in glucose and the resulting increase in insulin*. 

The science behind WMLE and citation links

Apple Tree Root Extract

“An apple a day keeps the doctor away” is a well known quote in Western cultures. Clinical observations throughout the last couple of centuries have shown apples offer many health benefits, but only in the last 150 years has that been actually studied.

The main ingredient responsible for glucose related control has been identified as Phloridzin. Phloridzin has been used as a pharmaceutical and tool for physiology research for over 150 years now.

Phloridzin’s principal pharmacological action is to produce renal glycosuria (loss of glucose into the urine) and to block intestinal glucose absorption*. This is accomplished via Sodium Linked Glucose Transports 1 and 2 (or SLGT1 and SLGT2).

SLGT1 is responsible for transport of glucose through the intestine (glucose absorption) and SLGT2 is responsible for the reabsorption of glucose in the kidneys (which prevents losing glucose into the urine)*.

The science behind ATRE and citation links

White Bean Extract

When people think of “Carb Blockers”, this is probably the supplement they are thinking about. Extracts from the common bean were first researched as α-amylase inhibitors in the late 1960’s, and have been further investigated since.

Inhibitors of α-amylase stop the digestion of starch by inhibiting their breakdown into smaller, absorbable sugars*. As a result, starches are passed undigested into the colon and therefore do not raise insulin levels*.

These inhibitors are popular as weight loss supplements because of how long they have been around and how much research one particular brand has done on α-amylase inhibitors used for weight reduction.

The science behind WBE and citation links

α-Lipoic Acid

ALA is a well investigated supplement with well documented antioxidant activities. However, further research into diabetes and metabolic syndrome has shown additional activities that are relevant for enhancing ketosis.

ALA, unlike most other AMPK activators, is a direct AMPK activator instead (current scientific thought is that it is activated via interactions with calcium transport)*.

One final way that ALA enhances ketosis: decreased insulin secretion*. ALA acts directly on the β cells that produce insulin in the pancreas, which causes them to decrease insulin production*.

In short, ALA decreases circulating glucose and insulin, decreases fat buildup in tissues, burns fat for energy, and decreases appetite and food intake*.

The science behind ALA and citation links

Magnolia Bark Extract

Magnolia officinalis has been used for millennia in Traditional Chinese Medicine. The two main bioactives in Magnolia are honokiol and magnolol. Both have similar properties, but honokiol has one major advantage over magnolol; honokiol is non-adipogenic.

Honokiol is a PPARγ partial agonist, which has a well-established role in the regulation of glucose and lipid metabolism*. However, the PPARγ agonists currently used for carbohydrate control (diabetes management) have the unwanted side-effects of weight gain, primarily by adipogenesis, or new fat cell development*.

This is where Honokiol really shines. Not only does it decrease circulating blood glucose by increasing transport into the muscle cells for use, but it does so without storing fat*. This is important for enhancing ketosis by limiting the insulin response by decreasing blood glucose.

PPARγ is also known to upregulate genes responsible for fatty acid oxidation (fat burning) while preventing the upregulation of lipogenic gene expression (new fat creation)*.

The science behind MBE and citation links

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent and disease.